Gene GPS1

All Male only Female only
Location (GRCh37):
chr17:80,008,567-80,015,346
Description:
G protein pathway suppressor 1 [Source:HGNC Symbol;Acc:4549]
Biotype
Protein coding
Nb components:
7
Ensembl:
ENSG00000169727
HGNC Symbol:
4549
MIM gene:
601934
Uniprot:
Q13098, A8K070, C9JFE4, J3KRY5, J3KRJ4, J3QS84, J3QL53, J3QS88, J3KSY1, J3QQP2, J3KSA5, J3QQX0, J3QLT0, A0A096LP07, J3QLE8, A0A096LPJ3, J3KTB0, J3KRE8
WikiGene:
2873
Median gene-level TPM by tissue (GTEx) [link]:

This plot shows tissues where the current gene is most expressed in GTEx to help contextualize phenotype associations.

Genetic associations QQ-plot

Inflation factor 𝜆=

This plot shows the distribution of observed association P-values compared to the expected distribution under the null hypothesis of no association (uniform distribution of P-values). Systematic deviation from the shaded region indicates statistical inflation that could be explained by pleiotropy.

Continuous variables

Outcome Id Description N -log10(P) P-Value P-Value (Bonferroni) Q-Value

* Values noted as 0 represent values smaller than the numerical floating point representation limit (< 2e-308 for this analysis).

Cardiovascular Endpoints

Outcome Id Description N cases N controls N excluded from controls -log10(P) P-Value P-Value (Bonferroni) Q-Value

Self Reported

Outcome Id Description N cases N controls N excluded from controls -log10(P) P-Value P-Value (Bonferroni) Q-Value

Phecodes

Outcome Id Description N cases N controls N excluded from controls -log10(P) P-Value P-Value (Bonferroni) Q-Value