Gene PARN

All Male only Female only
Location (GRCh37):
chr16:14,529,558-14,726,585
Description:
poly(A)-specific ribonuclease [Source:HGNC Symbol;Acc:8609]
Biotype
Protein coding
Nb components:
29
Ensembl:
ENSG00000140694
HGNC Symbol:
8609
MIM gene:
604212
Uniprot:
O95453, H3BRK1, H3BT23, F5H1Z4, H3BVG1, A0A494BZU6, A0A494C1G3, A0A494C0N0, A0A494C0Q2, A0A494C1K5, A0A494C156, A0A494BZW7, A0A494C0K5, A0A494C0Q6, A0A494C0W0, A0A494C0P9, A0A494C008, A0A494C002, A0A494C1N1
WikiGene:
5073
Median gene-level TPM by tissue (GTEx) [link]:

This plot shows tissues where the current gene is most expressed in GTEx to help contextualize phenotype associations.

Genetic associations QQ-plot

Inflation factor 𝜆=

This plot shows the distribution of observed association P-values compared to the expected distribution under the null hypothesis of no association (uniform distribution of P-values). Systematic deviation from the shaded region indicates statistical inflation that could be explained by pleiotropy.

Continuous variables

Outcome Id Description N -log10(P) P-Value P-Value (Bonferroni) Q-Value

* Values noted as 0 represent values smaller than the numerical floating point representation limit (< 2e-308 for this analysis).

Cardiovascular Endpoints

Outcome Id Description N cases N controls N excluded from controls -log10(P) P-Value P-Value (Bonferroni) Q-Value

Self Reported

Outcome Id Description N cases N controls N excluded from controls -log10(P) P-Value P-Value (Bonferroni) Q-Value

Phecodes

Outcome Id Description N cases N controls N excluded from controls -log10(P) P-Value P-Value (Bonferroni) Q-Value