Gene SF3B1

All Male only Female only
Location (GRCh37):
chr2:198,254,508-198,299,815
Description:
splicing factor 3b, subunit 1, 155kDa [Source:HGNC Symbol;Acc:10768]
Biotype
Protein coding
Nb components:
11
Ensembl:
ENSG00000115524
HGNC Symbol:
10768
MIM gene:
605590
Uniprot:
A0A494C1M2, B4DGZ4, F8WC19, H7C341, O75533
WikiGene:
23451
Median gene-level TPM by tissue (GTEx) [link]:

This plot shows tissues where the current gene is most expressed in GTEx to help contextualize phenotype associations.

Genetic associations QQ-plot

Inflation factor 𝜆=

Loading

This plot shows the distribution of observed association P-values compared to the expected distribution under the null hypothesis of no association (uniform distribution of P-values). Systematic deviation from the shaded region indicates statistical inflation that could be explained by pleiotropy.

Continuous variables

Outcome Id Description N -log10(P) P-Value P-Value (Bonferroni) Q-Value
Loading

* Values noted as 0 represent values smaller than the numerical floating point representation limit (< 2e-308 for this analysis).

Cardiovascular Endpoints

Outcome Id Description N cases N controls N excluded from controls -log10(P) P-Value P-Value (Bonferroni) Q-Value
Loading

Self Reported

Outcome Id Description N cases N controls N excluded from controls -log10(P) P-Value P-Value (Bonferroni) Q-Value
Loading

Phecodes

Outcome Id Description N cases N controls N excluded from controls -log10(P) P-Value P-Value (Bonferroni) Q-Value
Loading