Gene LAMA4

All Male only Female only
Location (GRCh37):
chr6:112,429,963-112,576,141
Description:
laminin, alpha 4 [Source:HGNC Symbol;Acc:6484]
Biotype
Protein coding
Nb components:
39
Ensembl:
ENSG00000112769
HGNC Symbol:
6484
MIM gene:
600133
MIM disease:
615235
Uniprot:
Q16363, A0A0A0MTC7, Q6LET9, A0A494C1K8, H0YAP9, A0A0A0MQS9, E5RHF3, E5RFD7, E5RK79, A0A494C139, E5RFQ2, H0Y351, H0YAQ5
WikiGene:
3910
Median gene-level TPM by tissue (GTEx) [link]:

This plot shows tissues where the current gene is most expressed in GTEx to help contextualize phenotype associations.

Genetic associations QQ-plot

Inflation factor 𝜆=

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This plot shows the distribution of observed association P-values compared to the expected distribution under the null hypothesis of no association (uniform distribution of P-values). Systematic deviation from the shaded region indicates statistical inflation that could be explained by pleiotropy.

Continuous variables

Outcome Id Description N -log10(P) P-Value P-Value (Bonferroni) Q-Value
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Values noted as 0 represent values smaller than the numerical floating point representation limit (< 2e-308 for this analysis).

Cardiovascular Endpoints

Outcome Id Description N cases N controls N excluded from controls -log10(P) P-Value P-Value (Bonferroni) Q-Value
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Self Reported

Outcome Id Description N cases N controls N excluded from controls -log10(P) P-Value P-Value (Bonferroni) Q-Value
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Phecodes

Outcome Id Description N cases N controls N excluded from controls -log10(P) P-Value P-Value (Bonferroni) Q-Value
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