Gene SIRPB1

All Male only Female only
Location (GRCh37):
chr20:1,544,167-1,600,707
Description:
signal-regulatory protein beta 1 [Source:HGNC Symbol;Acc:15928]
Biotype
Protein coding
Nb components:
33
Ensembl:
ENSG00000101307
HGNC Symbol:
15928
MIM gene:
603889
Uniprot:
O00241, Q5TFQ8, H3BU43, H9KV29, H3BRP9, H3BTT9, H3BQ21, H3BUW0, H3BSK5
WikiGene:
10326, 100653194
Median gene-level TPM by tissue (GTEx) [link]:

This plot shows tissues where the current gene is most expressed in GTEx to help contextualize phenotype associations.

Genetic associations QQ-plot

Inflation factor 𝜆=

This plot shows the distribution of observed association P-values compared to the expected distribution under the null hypothesis of no association (uniform distribution of P-values). Systematic deviation from the shaded region indicates statistical inflation that could be explained by pleiotropy.

Continuous variables

Outcome Id Description N -log10(P) P-Value P-Value (Bonferroni) Q-Value

* Values noted as 0 represent values smaller than the numerical floating point representation limit (< 2e-308 for this analysis).

Cardiovascular Endpoints

Outcome Id Description N cases N controls N excluded from controls -log10(P) P-Value P-Value (Bonferroni) Q-Value

Self Reported

Outcome Id Description N cases N controls N excluded from controls -log10(P) P-Value P-Value (Bonferroni) Q-Value

Phecodes

Outcome Id Description N cases N controls N excluded from controls -log10(P) P-Value P-Value (Bonferroni) Q-Value