Gene CLNS1A

All Male only Female only
Location (GRCh37):
chr11:77,225,981-77,348,850
Description:
chloride channel, nucleotide-sensitive, 1A [Source:HGNC Symbol;Acc:2080]
Biotype
Protein coding
Nb components:
30
Ensembl:
ENSG00000074201
HGNC Symbol:
2080
MIM gene:
602158
Uniprot:
P54105, E9PMI6, H0YEN9, E9PQ83, J3KN38, E9PJF4, U3KPU0
WikiGene:
1207
Median gene-level TPM by tissue (GTEx) [link]:

This plot shows tissues where the current gene is most expressed in GTEx to help contextualize phenotype associations.

Genetic associations QQ-plot

Inflation factor 𝜆=

This plot shows the distribution of observed association P-values compared to the expected distribution under the null hypothesis of no association (uniform distribution of P-values). Systematic deviation from the shaded region indicates statistical inflation that could be explained by pleiotropy.

Continuous variables

Outcome Id Description N -log10(P) P-Value P-Value (Bonferroni) Q-Value

* Values noted as 0 represent values smaller than the numerical floating point representation limit (< 2e-308 for this analysis).

Cardiovascular Endpoints

Outcome Id Description N cases N controls N excluded from controls -log10(P) P-Value P-Value (Bonferroni) Q-Value

Self Reported

Outcome Id Description N cases N controls N excluded from controls -log10(P) P-Value P-Value (Bonferroni) Q-Value

Phecodes

Outcome Id Description N cases N controls N excluded from controls -log10(P) P-Value P-Value (Bonferroni) Q-Value